Jump to content

Ribose 1-dehydrogenase (NADP+)

From Wikipedia, the free encyclopedia
ribose 1-dehydrogenase (NADP+)
Identifiers
EC no.1.1.1.115
CAS no.37250-46-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a ribose 1-dehydrogenase (NADP+) (EC 1.1.1.115) is an enzyme that catalyzes the chemical reaction

D-ribose + NADP+ + H2O D-ribonate + NADPH + H+

The three substrates of this enzyme are D-ribose, NADP+, and H2O, whereas its 3 products are D-ribonate, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is D-ribose:NADP+ 1-oxidoreductase. Other names in common use include D-ribose dehydrogenase (NADP+), NADP+-pentose-dehydrogenase, and ribose 1-dehydrogenase (NADP+).

References

[edit]
  • Scher BM, Horecker BL (1966). "Pentose metabolism in Candida. 3. The triphosphopyridine nucleotide-specific polyol dehydrogenase of Candida utilis". Arch. Biochem. Biophys. 116 (1): 117–28. doi:10.1016/0003-9861(66)90020-8. PMID 4381350.
  • Schiwara HW, Domschke W, Domagk GF (1968). "[Sugar dehydrogenases in mammalian liver. I. Differentiation of various sugar dehydrogenases from pig liver by disc electrophoresis and ion exchange chromatography]". Hoppe-Seyler's Z. Physiol. Chem. 349 (11): 1575–81. doi:10.1515/bchm2.1968.349.2.1575. PMID 4393642.