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List of β-lactam antibiotics

From Wikipedia, the free encyclopedia

PenamCarbapenamOxapenamPenemCarbapenemMonobactamCephemCarbacephemOxacephem
The β-lactam core structures. (A) A penam. (B) A carbapenam. (C) An oxapenam. (D) A penem. (E) A carbapenem. (F) A monobactam. (G) A cephem. (H) A carbacephem. (I) An oxacephem.

This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class. Antibiotics are listed alphabetically within their class or subclass by their nonproprietary name. If an antibiotic is a combination drug, both ingredients will be listed.

Penams

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Penicillin G
Amoxicillin

Narrow-spectrum

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β-lactamase-sensitive

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β-lactamase-resistant

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Broad spectrum

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Extended spectrum (Antipseudomonal)

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Carboxypenicillins

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Ureidopenicillins

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Cephems

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Cephalosporin C
Cefoxitin

First generation (moderate spectrum)

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Second generation (moderate spectrum)

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cefuroxime, cefaclor, cefprozil

With anti-Haemophilus activity

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With anti-anaerobic activity

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Third generation (broad spectrum)

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Fourth generation (broad spectrum)

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(With β-lactamase stability and enhanced activity against Gram-positive bacteria and Pseudomonas aeruginosa)

Fifth generation* (broad spectrum)

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(activity against MRSA and variably VRE. *Not universally accepted nomenclature. NO Antipseudomonal activity, mostly ceftriaxone coverage with additional MRSA and some VRE)

Carbapenems and penems

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(Broadest spectrum of β-lactam antibiotics)

Thienamycin

Monobactams

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Aztreonam

β-lactamase inhibitors

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Clavulanic Acid