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Butanal dehydrogenase

From Wikipedia, the free encyclopedia
butanal dehydrogenase
Identifiers
EC no.1.2.1.57
CAS no.116412-25-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a butanal dehydrogenase (EC 1.2.1.57) is an enzyme that catalyzes the chemical reaction

butanal + CoA + NAD(P)+ butanoyl-CoA + NAD(P)H + H+

The 4 substrates of this enzyme are butanal, CoA, NAD+, and NADP+, whereas its 4 products are butanoyl-CoA, NADH, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is butanal:NAD(P)+ oxidoreductase (CoA-acylating). This enzyme participates in butanoate metabolism.

References

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  • Palosaari NR, Rogers P (1988). "Purification and properties of the inducible coenzyme A-linked butyraldehyde dehydrogenase from Clostridium acetobutylicum". J. Bacteriol. 170 (7): 2971–6. PMC 211236. PMID 3384801.